William I. Nicholson, Alex C. Seastram, Saqib A. Iqbal, Benjamin G. Reed-Berendt, Louis C. Morrill* & Duncan L. Browne* ChemSusChem 2019 DOI: 10.1002/cssc.201902346[Open Access][Part of Wiley 'Hot Topic: Organocatalysis']
Wednesday, 6 November 2019
Another collaborative paper with the Morrill Group! This time we combine organocatalysis and ball-milling to deliver NHC catalysed acyl anion chemistry under milling conditions. This project took a while to land the appropriate conditions and then convert to substrate scope. Alex and Saqib were fresh faced MChem students at project outset, fortunately it did not put them off organic methodology and they are now pursuing PhDs, Morrill Group and Ingleson Group (Edinburgh), respectively. Good job by Will and Ben for seeing it through!