New Publication

Our work is published in Organic & Biomolecular Chemistry for the special edition in Contemporary Synthetic Chemistry in Drug Discovery The paper describes the preparation of a range of trifluoromethyl bearing isoxazole building blocks and their derivatisation through a variety of transformations, including intra- and intermolecular C-H arylation. Good job to all!

039 Synthesis of Trifluoromethylated Isoxazoles and Their Elaboration Through Inter- and Intra-molecular C-H Arylation

J.-S. Poh, C. García-Ruiz, A. Zuniga, F. Meroni, D. C. Blakemore, D. L. Browne*, S. V. Ley Org. Biomol. Chem 2016 10.1039/C6OB00970K

Duncan Visits Uruguay for a Workshop in Drug Discovery for Neglected Diseases and Malaria

Duncan teams up with Prof Simon Croft and Dr Vanessa Yardley (London School for Hygiene and Tropical Medicine) to visit Gloria Serra and her colleagues at the Facultad de Química, Universidad de la República de Uruguay, Montevideo. We discussed distributed manufacturing approaches and flow chemistry to combat Malaria, Chagas disease, Trypanosomiasis and Leishmaniasis.