Our invited work for the 'Emerging Investigators 2017 Themed Issue' is published in Green Chem. This paper describes our first work in the area of mechanochemical synthesis. Congratulations to Joey, Yerbol, Laura and Christiane!
Our invited book chapter on Fluorination Approaches is published in RSC Drug Discovery: Synthetic Methods in Drug Discovery. Thanks to Co-Author Paul Richardson (Pfizer, San Diego) and Editors David, Paul and Yvette
Our invited work is published in Journal of Flow Chemistry. The paper describes a continuous-flow process for the preparation of triazenes, whereby diazonium salts are generated and converted into their masked or protected triazene derivatives including the anticancer compounds Dacarbazine and Mitozolomide. Congratulations to Christiane, Yerbol Abdul and Martyn!
We are looking for a PhD student to work on organic methodology development. Start dates are October 2016 or Jan 2017. This position is open to UK and EU students and is fully funded.
please contact Duncan if you have any enquiries. http://courses.cardiff.ac.uk/funding/R2803.html
Our work is published in Chemical Communications. The paper describes a metal-free approach for the late-stage introduction of the important lipophilic hydrogen-bond donor motif, SCF2H. Good job Joey, Christiane and Stephen!
Our work is published in Organic & Biomolecular Chemistry for the special edition in Contemporary Synthetic Chemistry in Drug Discovery The paper describes the preparation of a range of trifluoromethyl bearing isoxazole building blocks and their derivatisation through a variety of transformations, including intra- and intermolecular C-H arylation. Good job to all!
Duncan teams up with Prof Simon Croft and Dr Vanessa Yardley (London School for Hygiene and Tropical Medicine) to visit Gloria Serra and her colleagues at the Facultad de Química, Universidad de la República de Uruguay, Montevideo. We discussed distributed manufacturing approaches and flow chemistry to combat Malaria, Chagas disease, Trypanosomiasis and Leishmaniasis.
The Browne lab welcomes new M.Phil. Student Yerbol Sagatov. Yerbol arrives on a Bolashak International Scholarship of the President of the Republic of Kazakhstan and has spent a year at the London School of Economics. Yerbol will eat you for breakfast!...... if you consist of eggs, beans, bacon, sausage, toast & hash browns, Yerbol likes to start the day with one (occasionally two!) British breakfasts.
The Browne lab welcomes Visiting Scholar Dr Abdul Hadi Aldmairi. Abdul obtained his PhD with Prof David Knight working on the synthesis of natural products using proton catalysed cyclisation reactions. Abdul will explore flow methods and organo-fluorine chemistry. Abdul likes to eat a lemon-a-day!
Duncan attends and gives a lecture at the 3rd in the series of UK conferences on Continuous Flow Processing. It was exciting to meet so many people and exciting to see that the industrialists continue to take the bull-by-the-horns with flow chemistry. It was also clear that the next generation of undergraduates and graduate students with training in continuous flow processing would be attractive to industry!
The group attend a busy 6th International Flow Chemistry Conference at Magdalene College, Cambridge. Where Duncan gave a lecture on the recent flow work from the group and Christiane and Joey presented posters. We enjoyed meeting many old and new faces and the live demo of remote control from the Ley Lab, nice job JSP and Daniel!