Gabriele Laudadio, Efstathios Barmpoutsis, Christiane Schotten, Lisa Struik, Sebastian Govearts, Duncan L. Browne & Timothy Noël* J. Am. Chem. Soc. 2019 DOI: 10.1021/jacs.9b02266
Tuesday, 26 March 2019
Christiane's contribution to the project in the Noël Research Group (NRG!) is published in JACS. Congratulations to everyone involved in this project, especially Gabriele and Tim who led this project expertly over the finish line, take-that sulfonamides!
Monday, 25 March 2019
Renan and Tom's work on the generation and interception of acylketenes under continuous flow conditions has been accepted for publication in Reaction Chemistry and Engineering. Great job by Renan and Tom on this one!
Renan Galaverna, Tom McBride, Julio C. Pastre & Duncan L. Browne* React. Chem. Eng. 2019 DOI: 10.1039/C9RE00072K
Thursday, 28 February 2019
We say farewell to Renan Galaverna who travels back to UNICAMP, Brazil - Renan is the coolest-cat we have met, both in the lab and on the football pitch! thanks for your hard work Renan!
Thursday, 31 January 2019
Group members Roddy Stark, Renan Galaverna and Will Nicholson presented their posters at the local RSC Organic Section meeting (South-West). Will received a runner-up prize for his poster concerning the mechanochemical formation of C-N bonds, congratulations Will!
Monday, 28 January 2019
Monday, 10 December 2018
Our collaborative article with the Pastre Group (UNICAMP, Brazil) on the continuous flow preparation of terpene-derived monomers is published in Reaction Chemistry and Engineering. Congratulations to Renan & Lucas on this one, thanks for involving us in this project.
Renan Galaverna, Lucas P. Fernandes, Duncan L. Browne & Julio C. Pastre* React. Chem. Eng 2019 DOI: 10.1039/C8RE00237A
Tuesday, 4 December 2018
Our collaborative article with the Melen Group is published in Chem Comm and describes the use of microwave reactors to enable a broader substrate scope in some catalytic borane reactions. Well done to Jamie and Lukas.
059- Unlocking the Catalytic Potential of Tris(3,4,5-trifluorophenyl) Borane with microwave Irradiation
Jamie L. Carden, Lukas J. Gierlichs, Duncan F. Wass, Duncan L. Browne & Rebecca L. Melen* Chem. Commun. 2019 DOI: 10.1039/C8CC09459D
Monday, 3 December 2018
Wednesday, 7 November 2018
Congratulations to Joey who passed his viva today and is the second member of the group to pass with a PhD, we are very proud of his achievements. Joey will join Bio-Techne (formerly Tocris) in Bristol - good luck Joey!
Thursday, 18 October 2018
Our article on altering reaction kinetics and chemoselectivity through mechanochemical processing is published in Angewandte Chemie Int. Ed. Congratulations to Joey and Mike for their careful work on this one!
Joseph L. Howard, Michael C. Brand & Duncan L. Browne* Angew. Chem. Int. Ed. 2018 , 57, 16104-16108[Open Access]
Tuesday, 2 October 2018
Monday, 1 October 2018
Welcome back to Andy Jones who joins for a PhD with financial support from KESS2. Andy's project will involve the development of catalytic processes employing mechanochemistry.
Wednesday, 19 September 2018
Our contribution to the Thieme Science of Synthesis; Flow Chemistry in Organic Synthesis volume is now published and is entitled Immobilized Reagents and Multistep Processes. It was a pleasure working with Steve and Matt again to bring this together!
057-Book Chapter Immobilized Reagents and Multistep Processes
Steven V. Ley, Duncan L. Browne & Matthew O'Brien Science of Synthesis, Flow Chemistry in Organic Synthesis, Chapter 9 2018, pages 273-312.
Tuesday, 18 September 2018
Our article on the mechanochemical Buchwald-Hartwig reaction is published as an invited contribution to the OBC 'New Talent' themed issue. Qun, Will and Andy have developed a robust air stable method for conducting this important C-N bond forming reaction, excellent job.
Qun Cao, William I. Nicholson, Andrew Jones & Duncan L. Browne* Org. Biomol. Chem. 2018 DOI: 10.1039/c8ob01781f[Open Access] ['New Talent' Issue]
Our collaborative work with the James group (Queens University, Belfast) on translating mechanochemical fluorination into a continuous twin-screw extrusion protocol has been published in Green Chemistry, Congratulations Qun and Joey and thanks to Debbie and Stuart
055- Translating solid state organic synthesis from a mixer mill to a continuous twin screw extruder
Qun Cao, Joseph L. Howard, Deborah E. Crawford, Stuart L. James* & Duncan L. Browne* Green Chem. 2018 DOI: 10.1039/c8gc02036a[Open Access]
Saturday, 21 July 2018
Our Work on the mechanical generation of organzincs and their subsequent participation in Negishi couplings using a ball-mill is accepted for publication in Angewandte Chemie, Congratulations to Qun, Joey and Emilie!
Qun Cao, Joseph L. Howard, Emilie Wheatley & Duncan L. Browne* Angew. Chem. Int. Ed. 2018, https://doi.org/10.1002/anie.201806480
Wednesday, 18 July 2018
Well done to all of our MChem students who graduated today with excellent degrees - It was a pleasure to have you around and good luck with your future pursuits. Special congratulations to Mike and Alex who received Outstanding 4th Year Mchem Awards!
|Michael Brand - next up - PhD with Prof. Andy Cooper @ Uni of Liverpool.|
|Saqib Iqbal - next up, PhD with Prof. Mike Ingleson @ Uni of Manchester.|
|Andrew Jones - next up, PhD DLB Group @ Cardiff Uni.|
|Emilie Wheatley - next up, PhD with Prof. Simon J. Meek, @ Uni. North Carolina, US.|
|Lukas Gierlichs (With Rebecca Melen) - next up, PhD with Rebecca Melen and DLB @ Cardiff Uni.|
|Timothy Lloyd (With Simon Pope) - next up, safety and compliance inspector for imaging equipment.|
|Alex Seastram (With Louis Morrill) - next up, PhD with Lous Morrill @ Cardiff Uni.|
Friday, 15 June 2018
The group welcomes our first visiting PhD from Brazil, Renan Galaverna joins from the group of Prof Julio Pastre from UNICAMP, Sao Paulo, Brazil. Renan's travel is sponsored by CNPQ and GCRF seed money.....he has arrived in good time for UK sun and the World Cup, both of which are quadrennial events!
Friday, 8 June 2018
Our collaborative work with Bruker on the design of a continuous flow-batch hybrid reactor for preparation of commodity chemicals using Flow NMR is accepted for the Barton Centennial issue of Tetrahedron, congratulations Cristiane, Joey, Rob and Anna!
053- A continuous flow-batch hybrid reactor for commodity chemical synthesis enabled by inline NMR and temperature monitoring
Christiane Schotten, Joseph L. Howard, Robert L. Jenkins, Anna Codina & Duncan L. Browne* Tetrahedron 2018,10.1016/j.tet.2018.05.070
Monday, 21 May 2018
Congratulation to Christiane who passed her viva today and is the first member of the group to pass with a PhD, we are very proud of her achievements. Christiane has just completed a Royal Society of Chemistry placement in the Nöel Research Group (http://www.noelresearchgroup.com/timothy-noel/) and will now join the group of Charlotte Willans (https://willans.leeds.ac.uk), Richard Bourne, Bao Nguyen and Nik Kapur @ University of Leeds as a Postdoc - good luck Christiane.
Wednesday, 7 March 2018
Our perspective article on Mechanochemistry for Molecular Synthesis is published in Chemical Science, well done Joey and Qun, we hope the community find this a stimulating perspective!
Joseph L. Howard, Qun Cao & Duncan L. Browne* Chem. Sci. 2018,10.1039/C7SC05371A
Tuesday, 20 February 2018
Our paper on the machine-assisted synthesis of follow-on compound libraries is published in Reaction Chemistry and Engineering, well done Christiane, Lisa & Lisa who have also made the antimigraine compound Zolmitriptan using this approach
Christiane Schotten, Lisa G. T. Leist, A. Lisa Semrau & Duncan L. Browne* React. Chem. Eng 2018,10.1039/C8RE00010G
Wednesday, 31 January 2018
The group bids farewell to Postdoc Qun Cao who was with us for an 11 month EPSRC funded position. Qun will now join the James group in Belfast - Thanks Qun for all of your hard work and dedication.
Friday, 8 December 2017
Our paper on Mechanochemical electrophilic fluorination of liquid beta-ketoesters is published in Tetrahedron, well done Joey and Yerbol!
Joseph L. Howard,Yerbol Sagatov & Duncan L. Browne* Tetrahedron 2018,https://doi.org/10.1016/j.tet.2017.11.066
Thursday, 14 September 2017
Our paper on multistep mechanochemistry is published in the Mechanochemistry themed issue at Beilstein Journal of Organic Chemistry, well done Joey, Will and Yerbol
Joseph L. Howard, William Nicholson, Yerbol Sagatov & Duncan L. Browne* Beilstein J. Org. Chem. 2017,13 1950-1956
Wednesday, 9 August 2017
Our paper with the Kühn & Casini groups on the synthesis and biological properties of tridentate cyclometalated gold (III) complexes is published in Bioorganic and Medicinal Chemistry.
048- Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes
Sophie Jürgens, Valeria Scalcon, Natalia Estrada-Ortiz, Alessandra Folda, Federica Tonolo, Christian Jandl, Duncan L. Browne, Maria Pia Rigobello, Fritz E. Kühn*, Angela Casini*, Bioorg. Med. Chem. 2017,25 5452-5460
Tuesday, 13 June 2017
Monday, 22 May 2017
Our collaborative paper with the Pope, Platts and Beames groups on Machine-assisted preparation of tunable luminescent materials is published in Chemistry a European Journal, well done Lara and Christiane
047- From Ligand to Phosphor: Rapid, Machine-Assisted Syntheses of Substituted Iridium(III)-Pyrazolate Complexes with Tuneable Luminescence
Lara M. Groves, Christiane Schotten, J. Beames, J. A. Platts, Simon J. Coles, Peter N Horton, D. L. Browne* & S. J. A. Pope*, Chem. Eur. J. 2017, DOI: 10.1002/chem.201701551
Our collaborative paper with the Melen group on Exploring Multistep Continuous-Flow Hydrosilylation Reactions Catalyzed by Tris(pentafluorophenyl)borane is published in Advanced Synthesis & Catalysis with a VIP stamp! well done to Lewis, Joey, Stefan & Louis
046- Exploring Multistep Continuous-Flow Hydrosilylation Reactions Catalyzed by Tris(pentafluorophenyl)borane
Lewis C. Wilkins, Joseph L. Howard, Stefan Berger, Louis Frentzel-Beyme, D. L. Browne* & R. L. Melen* Adv. Synth. Catalyst 2017, 10.1002/adsc.201700349.
Thursday, 4 May 2017
Our book chapter is published in Comprehensive Medicinal Chemistry 3rd Edition; Volume 1 The chapter is titled Continuous Flow Processing as a Tool for Medicinal Chemical Synthesis. Good job Joey and Christiane!
D. L. Browne*, Joseph L. Howard & Christiane Schotten Comprehensive Medicinal Chemistry, 3rd Edition; Volume 1, Elsevier, 2017, pages 1-50.