Our invited work is published in Journal of Flow Chemistry. The paper describes a continuous-flow process for the preparation of triazenes, whereby diazonium salts are generated and converted into their masked or protected triazene derivatives including the anticancer compounds Dacarbazine and Mitozolomide. Congratulations to Christiane, Yerbol Abdul and Martyn!
We are looking for a PhD student to work on organic methodology development. Start dates are October 2016 or Jan 2017. This position is open to UK and EU students and is fully funded.
please contact Duncan if you have any enquiries. http://courses.cardiff.ac.uk/funding/R2803.html
Our work is published in Chemical Communications. The paper describes a metal-free approach for the late-stage introduction of the important lipophilic hydrogen-bond donor motif, SCF2H. Good job Joey, Christiane and Stephen!
Our work is published in Organic & Biomolecular Chemistry for the special edition in Contemporary Synthetic Chemistry in Drug Discovery The paper describes the preparation of a range of trifluoromethyl bearing isoxazole building blocks and their derivatisation through a variety of transformations, including intra- and intermolecular C-H arylation. Good job to all!
The Browne lab welcomes new M.Phil. Student Yerbol Sagatov. Yerbol arrives on a Bolashak International Scholarship of the President of the Republic of Kazakhstan and has spent a year at the London School of Economics. Yerbol will eat you for breakfast!...... if you consist of eggs, beans, bacon, sausage, toast & hash browns, Yerbol likes to start the day with one (occasionally two!) British breakfasts.
The Browne lab welcomes Visiting Scholar Dr Abdul Hadi Aldmairi. Abdul obtained his PhD with Prof David Knight working on the synthesis of natural products using proton catalysed cyclisation reactions. Abdul will explore flow methods and organo-fluorine chemistry. Abdul likes to eat a lemon-a-day!
Duncan attends and gives a lecture at the 3rd in the series of UK conferences on Continuous Flow Processing. It was exciting to meet so many people and exciting to see that the industrialists continue to take the bull-by-the-horns with flow chemistry. It was also clear that the next generation of undergraduates and graduate students with training in continuous flow processing would be attractive to industry!
The group attend a busy 6th International Flow Chemistry Conference at Magdalene College, Cambridge. Where Duncan gave a lecture on the recent flow work from the group and Christiane and Joey presented posters. We enjoyed meeting many old and new faces and the live demo of remote control from the Ley Lab, nice job JSP and Daniel!
The Browne Group welcomes PhD Student David J. Cutress who joins the Browne, and Brophy (Aberystwyth) groups. Davids PhD is sponsored by the NRN Life Science Research Network Wales .
David has the exciting/daunting (delete as appropriate) task of designing, synthesising and testing compounds that may inhibit liver fluke (a liver parasite). Davids project is entitled 'Towards validation of an immune suppressor protein from liver fluke as a drug target'.
David studied genetics and biochemistry at Aberystwyth University IBERS receiving a first class degree along with the 'Society of Biology Top Student Award' after finishing his degree he was granted the 'Walter Idris Jones' bursary for a joint lab based project with the Geology and Microbiology departments studying novel glacial microbe species, in particular exosome vesicle activities.
The Browne Group welcomes MChem Student Toby Sydenham who joins the Browne, Fallis and Amaroso groups for his final year project.....3 supervisors, I didn't think anyone would pick that project. Toby does an excellent James Blunt impression!
The Browne Group welcomes Stefan Burger an ERASMUS student coming from Technische Universität München (TUM) and Louis Frentzel-Beyme an ERASMUS student coming from Ruhr-Universität Bochum. Stefan and Louis join both the Browne and Melen groups for joint collaborative projects.
The Browne lab welcomes Summer student Alex Bukvic who will work on an industrially funded summer studentship. Aside from chemistry Alex enjoys white-water rafting in the south of France, although wouldn't recommend driving in a car that is at the end of its life!
DLB Gives a Lecture at the RSC South-West Regional Meeting in Reading. Cardiff Attendees were Joey, Christiane and members of the Elliott and Wirth Groups. Thanks to Mark Elliott for stepping up to the bus-driving plate and getting everyone to the gig on time! Congratulations to Rich (Wirth Group) for 1st prize poster.
The Browne Research Group welcomes Christiane Schotten who joins as the first PhD student! Congratulations and good luck to her on her chemical adventures, no pressure! Christiane joins from RWTH Aachen where during her B.Sc. she conducted a final year research project with Prof. Palkovits. For her M.Sc. degree she carried our projects with Prof. Wessling, Prof. Liauw, Prof. Bolm, Prof. Leitner and Prof. Lapkin (University of Cambridge). Christiane enjoys swimming, singing and board games and has promised to supply biscuits from her home town!
The house build is complete and DLB’s better half and mini-B's relocate to Wales to be students of Welsh culture and Language, Croeso i Cymru, bring on the castles. He waves goodbye to the thoroughly recommendable Elano B&B, and the thoroughly unrecommendable weekend commute from Cambridge!
Duncan delivers a new lecture course on Enabling Technologies for Organic Synthesis.
The course was part of the module CH3404 Asymmetric Synthesis of Pharmaceuticals and Natural Products for the fourth year students. The course covers practical considerations and the pros and cons of running reactions under Microwave, Electrochemical, Photochemical and Continuous flow conditions.
Welcome to Joey Howard who becomes the first Browne Research Group member. Joey joins from Cambridge as an MPhil. student. Good Luck Joey!
Note added following the Christmas Party 2015 - Joey has a photographic knowledge of the UK's motorway network!