Monday, 28 January 2019

Farewell to PDRA Yin

We say farewell to PDRA Yin JieXiang who travels to Australia to be with his young family - good luck to you all on your adventure and thanks for your hard work and dedication.

Monday, 10 December 2018

New Publication

Our collaborative article with the Pastre Group (UNICAMP, Brazil) on the continuous flow preparation of terpene-derived monomers is published in Reaction Chemistry and Engineering. Congratulations to Renan & Lucas on this one, thanks for involving us in this project.

Renan Galaverna, Lucas P. Fernandes, Duncan L. Browne & Julio C. Pastre* React. Chem. Eng 2019 DOI: 10.1039/C8RE00237A

Tuesday, 4 December 2018

New Publication

Our collaborative article with the Melen Group is published in Chem Comm and describes the use of microwave reactors to enable a broader substrate scope in some catalytic borane reactions. Well done to Jamie and Lukas.

Jamie L. Carden, Lukas J. Gierlichs, Duncan F. Wass, Duncan L. Browne & Rebecca L. Melen* Chem. Commun. 2019 DOI: 10.1039/C8CC09459D

Wednesday, 7 November 2018

Congratulations to Dr Howard

Congratulations to Joey who passed his viva today and is the second member of the group to pass with a PhD, we are very proud of his achievements. Joey will join Bio-Techne (formerly Tocris) in Bristol - good luck Joey!

Thursday, 18 October 2018

New Publication

Our article on altering reaction kinetics and chemoselectivity through mechanochemical processing is published in Angewandte Chemie Int. Ed. Congratulations to Joey and Mike for their careful work on this one!

Joseph L. Howard, Michael C. Brand & Duncan L. Browne* Angew. Chem. Int. Ed. 2018 , 57, 16104-16108

[Open Access]

Tuesday, 2 October 2018

Welcome to the new MChem Students

The group welcomes our new MChem students; Karl Griffiths (Flow), Oliver Kershaw (Flow) & Calum Parsons (Mechano).

Monday, 1 October 2018

Welcome to New PhD Student Andrew Jones

Welcome back to Andy Jones who joins for a PhD with financial support from KESS2. Andy's project will involve the development of catalytic processes employing mechanochemistry.

Wednesday, 19 September 2018

New Publication - Book Chapter

Our contribution to the Thieme Science of Synthesis; Flow Chemistry in Organic Synthesis volume is now published and is entitled Immobilized Reagents and Multistep Processes. It was a pleasure working with Steve and Matt again to bring this together!

Steven V. Ley, Duncan L. Browne & Matthew O'Brien Science of Synthesis, Flow Chemistry in Organic Synthesis, Chapter 9 2018, pages 273-312.

Tuesday, 18 September 2018

New Publication

Our article on the mechanochemical Buchwald-Hartwig reaction is published as an invited contribution to the OBC 'New Talent' themed issue. Qun, Will and Andy have developed a robust air stable method for conducting this important C-N bond forming reaction, excellent job.

Qun Cao, William I. Nicholson, Andrew Jones & Duncan L. Browne* Org. Biomol. Chem. 2018 DOI: 10.1039/c8ob01781f

[Open Access] ['New Talent' Issue]

New Publication

Our collaborative work with the James group (Queens University, Belfast) on translating mechanochemical fluorination into a continuous twin-screw extrusion protocol has been published in Green Chemistry, Congratulations Qun and Joey and thanks to Debbie and Stuart

Qun Cao, Joseph L. Howard, Deborah E. Crawford, Stuart L. James* & Duncan L. Browne* Green Chem. 2018 DOI: 10.1039/c8gc02036a

[Open Access]

Saturday, 21 July 2018

New Publication

Our Work on the mechanical generation of organzincs and their subsequent participation in Negishi couplings using a ball-mill is accepted for publication in Angewandte Chemie, Congratulations to Qun, Joey and Emilie!

Qun Cao, Joseph L. Howard, Emilie Wheatley & Duncan L. Browne* Angew. Chem. Int. Ed. 2018, https://doi.org/10.1002/anie.201806480

Wednesday, 18 July 2018

Congratulations to our MChems Students

Well done to all of our MChem students who graduated today with excellent degrees - It was a pleasure to have you around and good luck with your future pursuits. Special congratulations to Mike and Alex who received Outstanding 4th Year Mchem Awards!

Michael Brand - next up - PhD with Prof. Andy Cooper @ Uni of Liverpool.
Saqib Iqbal - next up, PhD with Prof. Mike Ingleson @ Uni of Manchester.
Andrew Jones - next up, PhD DLB Group @ Cardiff Uni.
Emilie Wheatley - next up, PhD with Prof. Simon J. Meek, @ Uni. North Carolina, US.
Lukas Gierlichs (With Rebecca Melen) - next up, PhD with Rebecca Melen and DLB @ Cardiff Uni.
Timothy Lloyd (With Simon Pope) - next up, safety and compliance inspector for imaging equipment.
Alex Seastram (With Louis Morrill) - next up, PhD with Lous Morrill @ Cardiff Uni.

Friday, 15 June 2018

Welcome to Renan Galverna

The group welcomes our first visiting PhD from Brazil, Renan Galaverna joins from the group of Prof Julio Pastre from UNICAMP, Sao Paulo, Brazil. Renan's travel is sponsored by CNPQ and GCRF seed money.....he has arrived in good time for UK sun and the World Cup, both of which are quadrennial events!

Friday, 8 June 2018

New Publication

Our collaborative work with Bruker on the design of a continuous flow-batch hybrid reactor for preparation of commodity chemicals using Flow NMR is accepted for the Barton Centennial issue of Tetrahedron, congratulations Cristiane, Joey, Rob and Anna!

Christiane Schotten, Joseph L. Howard, Robert L. Jenkins, Anna Codina & Duncan L. Browne* Tetrahedron 2018,10.1016/j.tet.2018.05.070

Monday, 21 May 2018

Congratulations to Dr Schotten

Congratulation to Christiane who passed her viva today and is the first member of the group to pass with a PhD, we are very proud of her achievements. Christiane has just completed a Royal Society of Chemistry placement in the Nöel Research Group (http://www.noelresearchgroup.com/timothy-noel/) and will now join the group of Charlotte Willans (https://willans.leeds.ac.uk), Richard Bourne, Bao Nguyen and Nik Kapur @ University of Leeds as a Postdoc - good luck Christiane.

Wednesday, 7 March 2018

New Publication

Our perspective article on Mechanochemistry for Molecular Synthesis is published in Chemical Science, well done Joey and Qun, we hope the community find this a stimulating perspective!

Joseph L. Howard, Qun Cao & Duncan L. Browne* Chem. Sci. 2018,10.1039/C7SC05371A

Tuesday, 20 February 2018

New Publication

Our paper on the machine-assisted synthesis of follow-on compound libraries is published in Reaction Chemistry and Engineering, well done Christiane, Lisa & Lisa who have also made the antimigraine compound Zolmitriptan using this approach

Christiane Schotten, Lisa G. T. Leist, A. Lisa Semrau & Duncan L. Browne* React. Chem. Eng 2018,10.1039/C8RE00010G

Wednesday, 31 January 2018

Farewell to Qun

The group bids farewell to Postdoc Qun Cao who was with us for an 11 month EPSRC funded position. Qun will now join the James group in Belfast - Thanks Qun for all of your hard work and dedication.

Friday, 8 December 2017

New Publication

Our paper on Mechanochemical electrophilic fluorination of liquid beta-ketoesters is published in Tetrahedron, well done Joey and Yerbol!

Joseph L. Howard,Yerbol Sagatov & Duncan L. Browne* Tetrahedron 2018,https://doi.org/10.1016/j.tet.2017.11.066

Thursday, 14 September 2017

New Publication

Our paper on multistep mechanochemistry is published in the Mechanochemistry themed issue at Beilstein Journal of Organic Chemistry, well done Joey, Will and Yerbol

Joseph L. Howard, William Nicholson, Yerbol Sagatov & Duncan L. Browne* Beilstein J. Org. Chem. 2017,13 1950-1956

Wednesday, 9 August 2017

New Publication

Our paper with the Kühn & Casini groups on the synthesis and biological properties of tridentate cyclometalated gold (III) complexes is published in Bioorganic and Medicinal Chemistry.

Sophie Jürgens, Valeria Scalcon, Natalia Estrada-Ortiz, Alessandra Folda, Federica Tonolo, Christian Jandl, Duncan L. Browne, Maria Pia Rigobello, Fritz E. Kühn*, Angela Casini*, Bioorg. Med. Chem. 2017,25 5452-5460

Tuesday, 13 June 2017

New Member - Yin Jiexiang

The Browne Group welcomes new Postdoc Yin Jiexiang. Yin joins our LSRNW funded project on Radiotracers, in a collaboration with Dr Ian Fallis. Yin obtained his PhD under the guidance of Chris Hyland at University of Wollongong Australia before joining us in Cardiff.

Monday, 22 May 2017

New Publication

Our collaborative paper with the Pope, Platts and Beames groups on Machine-assisted preparation of tunable luminescent materials is published in Chemistry a European Journal, well done Lara and Christiane

Lara M. Groves, Christiane Schotten, J. Beames, J. A. Platts, Simon J. Coles, Peter N Horton, D. L. Browne* & S. J. A. Pope*, Chem. Eur. J. 2017, DOI: 10.1002/chem.201701551

New Publication

Our collaborative paper with the Melen group on Exploring Multistep Continuous-Flow Hydrosilylation Reactions Catalyzed by Tris(pentafluorophenyl)borane is published in Advanced Synthesis & Catalysis with a VIP stamp! well done to Lewis, Joey, Stefan & Louis

Lewis C. Wilkins, Joseph L. Howard, Stefan Berger, Louis Frentzel-Beyme, D. L. Browne* & R. L. Melen* Adv. Synth. Catalyst 2017, 10.1002/adsc.201700349.

Thursday, 4 May 2017

New Publication

Our book chapter is published in Comprehensive Medicinal Chemistry 3rd Edition; Volume 1 The chapter is titled Continuous Flow Processing as a Tool for Medicinal Chemical Synthesis. Good job Joey and Christiane!

D. L. Browne*, Joseph L. Howard & Christiane Schotten Comprehensive Medicinal Chemistry, 3rd Edition; Volume 1, Elsevier, 2017, pages 1-50.

Tuesday, 4 April 2017

New Publication

Our invited minireview/concept article for the 'Emerging Investigators 2017 Themed Issue' is published in React. Chem. Eng. This paper describes the concept of distributed chemical manufacturing to tackle the geographically localised development of resistant strains of pathogens. Good job Joey and Christiane! and Thanks To Simon Croft and Vanessa Yardley at the London School of Hygiene and Tropical Medicine.

Joseph L. Howard, Christiane Schotten & D. L. Browne* React. Chem. Eng. 2017, 10.1039/C7RE00034K.

Thursday, 30 March 2017

Award Nomination for Christiane

Congratulation to Christiane Schotten who has been nominated and shortlisted for an ELSA (Enriching Student Lives Award!) for Academic Representative of the Year in the college of Physical Sciences and Engineering....If you thought she was already a force to be reckoned with.....now she has a nomination behind her!

"You are recognised for your outstanding dedication to enriching the student experience. We were overwhelmed by the strength and quality of the nominations. It is a testament to your own commitment that you have not only been nominated but shortlisted for an award"......Well done! and thanks to those that nominated Christiane.

Wednesday, 1 March 2017

New Member - Dr Qun Cao

The Browne Group welcomes new Postdoc Qun Cao. Qun joins our EPSRC funded project in mechanochemistry. Qun obtained his PhD under the guidance of Mark Muldoon at Queens University Belfast and then carried out a Postdoctoral position with Victor Sans Sangorrin at the University of Nottingham before joining us in Cardiff.

Thursday, 2 February 2017

Poster Award

Congratulations to Joey Howard who received a poster prize at the South and West RSC Synthesis meeting in Bath yesterday for his poster on Liquid Assisted Grinding effects for mechanochemical fluorination!

Wednesday, 14 December 2016

New Publication

Our invited work for the 'Emerging Investigators 2017 Themed Issue' is published in Green Chem. This paper describes our first work in the area of mechanochemical synthesis. Congratulations to Joey, Yerbol, Laura and Christiane!

Joseph L. Howard, Yerbol Sagatov, Laura Repusseau, Christiane Schotten & D. L. Browne* Green Chem. 2017, 10.1039/C6GC03139K.