Saturday, 21 July 2018

New Publication

Our Work on the mechanical generation of organzincs and their subsequent participation in Negishi couplings using a ball-mill is accepted for publication in Angewandte Chemie, Congratulations to Qun, Joey and Emilie!

Qun Cao, Joseph L. Howard, Emilie Wheatley & Duncan L. Browne* Angew. Chem. Int. Ed. 2018,

Wednesday, 18 July 2018

Congratulations to our MChems Students

Well done to all of our MChem students who graduated today with excellent degrees - It was a pleasure to have you around and good luck with your future pursuits. Special congratulations to Mike and Alex who received Outstanding 4th Year Mchem Awards!

Michael Brand - next up - PhD with Prof. Andy Cooper @ Uni of Liverpool.
Saqib Iqbal - next up, PhD with Prof. Mike Ingleson @ Uni of Manchester.
Andrew Jones - next up, PhD DLB Group @ Cardiff Uni.
Emilie Wheatley - next up, PhD with Prof. Simon J. Meek, @ Uni. North Carolina, US.
Lukas Gierlichs (With Rebecca Melen) - next up, PhD with Rebecca Melen and DLB @ Cardiff Uni.
Timothy Lloyd (With Simon Pope) - next up, safety and compliance inspector for imaging equipment.
Alex Seastram (With Louis Morrill) - next up, PhD with Lous Morrill @ Cardiff Uni.

Friday, 8 June 2018

New Publication

Our collaborative work with Bruker on the design of a continuous flow-batch hybrid reactor for preparation of commodity chemicals using Flow NMR is accepted for the Barton Centennial issue of Tetrahedron, congratulations Cristiane, Joey, Rob and Anna!

Christiane Schotten, Joseph L. Howard, Robert L. Jenkins, Anna Codina & Duncan L. Browne* Tetrahedron 2018,10.1016/j.tet.2018.05.070

Monday, 21 May 2018

Congratulations to Dr Schotten

Congratulation to Christiane who passed her viva today and is the first member of the group to pass with a PhD, we are very proud of her achievements. Christiane has just completed a Royal Society of Chemistry placement in the Nöel Research Group ( and will now join the group of Charlotte Willans (, Richard Bourne, Bao Nguyen and Nik Kapur @ University of Leeds as a Postdoc - good luck Christiane.

Wednesday, 7 March 2018

New Publication

Our perspective article on Mechanochemistry for Molecular Synthesis is published in Chemical Science, well done Joey and Qun, we hope the community find this a stimulating perspective!

Joseph L. Howard, Qun Cao & Duncan L. Browne* Chem. Sci. 2018,10.1039/C7SC05371A

Tuesday, 20 February 2018

New Publication

Our paper on the machine-assisted synthesis of follow-on compound libraries is published in Reaction Chemistry and Engineering, well done Christiane, Lisa & Lisa who have also made the antimigraine compound Zolmitriptan using this approach

Christiane Schotten, Lisa G. T. Leist, A. Lisa Semrau & Duncan L. Browne* React. Chem. Eng 2018,10.1039/C8RE00010G

Wednesday, 31 January 2018

Farewell to Qun

The group bids farewell to Postdoc Qun Cao who was with us for an 11 month EPSRC funded position. Qun will now join the James group in Belfast - Thanks Qun for all of your hard work and dedication.

Friday, 8 December 2017

New Publication

Our paper on Mechanochemical electrophilic fluorination of liquid beta-ketoesters is published in Tetrahedron, well done Joey and Yerbol!

Joseph L. Howard,Yerbol Sagatov & Duncan L. Browne* Tetrahedron 2018,

Thursday, 14 September 2017

New Publication

Our paper on multistep mechanochemistry is published in the Mechanochemistry themed issue at Beilstein Journal of Organic Chemistry, well done Joey, Will and Yerbol

Joseph L. Howard, William Nicholson, Yerbol Sagatov & Duncan L. Browne* Beilstein J. Org. Chem. 2017,13 1950-1956

Wednesday, 9 August 2017

New Publication

Our paper with the Kühn & Casini groups on the synthesis and biological properties of tridentate cyclometalated gold (III) complexes is published in Bioorganic and Medicinal Chemistry.

Sophie Jürgens, Valeria Scalcon, Natalia Estrada-Ortiz, Alessandra Folda, Federica Tonolo, Christian Jandl, Duncan L. Browne, Maria Pia Rigobello, Fritz E. Kühn*, Angela Casini*, Bioorg. Med. Chem. 2017,25 5452-5460

Tuesday, 13 June 2017

New Member - Yin Jiexiang

The Browne Group welcomes new Postdoc Yin Jiexiang. Yin joins our LSRNW funded project on Radiotracers, in a collaboration with Dr Ian Fallis. Yin obtained his PhD under the guidance of Chris Hyland at University of Wollongong Australia before joining us in Cardiff.

Monday, 22 May 2017

New Publication

Our collaborative paper with the Pope, Platts and Beames groups on Machine-assisted preparation of tunable luminescent materials is published in Chemistry a European Journal, well done Lara and Christiane

Lara M. Groves, Christiane Schotten, J. Beames, J. A. Platts, Simon J. Coles, Peter N Horton, D. L. Browne* & S. J. A. Pope*, Chem. Eur. J. 2017, DOI: 10.1002/chem.201701551

New Publication

Our collaborative paper with the Melen group on Exploring Multistep Continuous-Flow Hydrosilylation Reactions Catalyzed by Tris(pentafluorophenyl)borane is published in Advanced Synthesis & Catalysis with a VIP stamp! well done to Lewis, Joey, Stefan & Louis

Lewis C. Wilkins, Joseph L. Howard, Stefan Berger, Louis Frentzel-Beyme, D. L. Browne* & R. L. Melen* Adv. Synth. Catalyst 2017, 10.1002/adsc.201700349.

Thursday, 4 May 2017

New Publication

Our book chapter is published in Comprehensive Medicinal Chemistry 3rd Edition; Volume 1 The chapter is titled Continuous Flow Processing as a Tool for Medicinal Chemical Synthesis. Good job Joey and Christiane!

D. L. Browne*, Joseph L. Howard & Christiane Schotten Comprehensive Medicinal Chemistry, 3rd Edition; Volume 1, Elsevier, 2017, pages 1-50.

Tuesday, 4 April 2017

New Publication

Our invited minireview/concept article for the 'Emerging Investigators 2017 Themed Issue' is published in React. Chem. Eng. This paper describes the concept of distributed chemical manufacturing to tackle the geographically localised development of resistant strains of pathogens. Good job Joey and Christiane! and Thanks To Simon Croft and Vanessa Yardley at the London School of Hygiene and Tropical Medicine.

Joseph L. Howard, Christiane Schotten & D. L. Browne* React. Chem. Eng. 2017, 10.1039/C7RE00034K.

Thursday, 30 March 2017

Award Nomination for Christiane

Congratulation to Christiane Schotten who has been nominated and shortlisted for an ELSA (Enriching Student Lives Award!) for Academic Representative of the Year in the college of Physical Sciences and Engineering....If you thought she was already a force to be reckoned she has a nomination behind her!

"You are recognised for your outstanding dedication to enriching the student experience. We were overwhelmed by the strength and quality of the nominations. It is a testament to your own commitment that you have not only been nominated but shortlisted for an award"......Well done! and thanks to those that nominated Christiane.

Wednesday, 1 March 2017

New Member - Dr Qun Cao

The Browne Group welcomes new Postdoc Qun Cao. Qun joins our EPSRC funded project in mechanochemistry. Qun obtained his PhD under the guidance of Mark Muldoon at Queens University Belfast and then carried out a Postdoctoral position with Victor Sans Sangorrin at the University of Nottingham before joining us in Cardiff.

Thursday, 2 February 2017

Poster Award

Congratulations to Joey Howard who received a poster prize at the South and West RSC Synthesis meeting in Bath yesterday for his poster on Liquid Assisted Grinding effects for mechanochemical fluorination!

Wednesday, 14 December 2016

New Publication

Our invited work for the 'Emerging Investigators 2017 Themed Issue' is published in Green Chem. This paper describes our first work in the area of mechanochemical synthesis. Congratulations to Joey, Yerbol, Laura and Christiane!

Joseph L. Howard, Yerbol Sagatov, Laura Repusseau, Christiane Schotten & D. L. Browne* Green Chem. 2017, 10.1039/C6GC03139K.

Friday, 2 December 2016

Group News

Shannon finishes her research visit to the group today and returns to Singapore - thanks for all of your hard work Shannon!

Friday, 25 November 2016

Thieme Chemistry Journal Awardee 2017

The group has received recognition through a Thieme Chemistry Journal Award 2017, thanks to the group for their continued hardwork.

Wednesday, 2 November 2016

Flow Chemistry Congress - Miami

Duncan Talks at the Flow Chemistry Society Congress in Miami. It was great to hear about the excellent work from colleagues in the US!

Thursday, 1 September 2016

New Publication

Our invited book chapter on Fluorination Approaches is published in RSC Drug Discovery: Synthetic Methods in Drug Discovery. Thanks to Co-Author Paul Richardson (Pfizer, San Diego) and Editors David, Paul and Yvette

D. L. Browne* & Paul Richardson* Synthetic Methods in Drug Discovery, Chapter 15: Fluorination Approaches, Volume 2, RSC, 2016, pages 263-370.

Sunday, 14 August 2016


Duncan and Stefano Leoni visit Julio Pastre, Alfredo Sigoli and the rest of the faculty at the institute of chemistry, UNICAMP Brazil

Wednesday, 3 August 2016

New Publication

Our invited work is published in Journal of Flow Chemistry. The paper describes a continuous-flow process for the preparation of triazenes, whereby diazonium salts are generated and converted into their masked or protected triazene derivatives including the anticancer compounds Dacarbazine and Mitozolomide. Congratulations to Christiane, Yerbol Abdul and Martyn!

C. Schotten, A. H. Aldmairi, Y. Sagatov, M. Shepherd, D. L. Browne* J. Flow Chem. 2016 10.1556/1846.2016.00025

Friday, 1 July 2016

PDRA Position available - 12 month LSRNW funded PDRA position available in our research group (Joint With Dr Ian Fallis)

We are looking for a Postdoc to work on an organic methodology project. Start date is October 2016 (some flexibility may be possible for exceptional candidates). This position is open to UK and EU students and is fully funded. Please contact Duncan or Ian if you have any enquiries. Formal details of the application process can be found at

PDRA Position available - 11 month EPSRC funded PDRA position available in our research group

We are looking for a Postdoc to work on an organic methodology project. Start date is October 2016 (some flexibility may be possible for exceptional candidates). This position is open to UK and EU students and is fully funded. Please contact Duncan if you have any enquiries. Formal applications can be found at

Thursday, 30 June 2016

PhD Position available - 3.5 year PhD studentship available in our research group

We are looking for a PhD student to work on organic methodology development. Start dates are October 2016 or Jan 2017. This position is open to UK and EU students and is fully funded. please contact Duncan if you have any enquiries.

Monday, 20 June 2016

New Publication

Our work is published in Chemical Communications. The paper describes a metal-free approach for the late-stage introduction of the important lipophilic hydrogen-bond donor motif, SCF2H. Good job Joey, Christiane and Stephen!

J. L. Howard, C. Schotten, S. T. Alston, D. L. Browne* Chem. Commun. 2016 10.1039/C6CC02693A

Friday, 20 May 2016

New Publication

Our work is published in Organic & Biomolecular Chemistry for the special edition in Contemporary Synthetic Chemistry in Drug Discovery The paper describes the preparation of a range of trifluoromethyl bearing isoxazole building blocks and their derivatisation through a variety of transformations, including intra- and intermolecular C-H arylation. Good job to all!

J.-S. Poh, C. García-Ruiz, A. Zuniga, F. Meroni, D. C. Blakemore, D. L. Browne*, S. V. Ley Org. Biomol. Chem 2016 10.1039/C6OB00970K

Monday, 9 May 2016

Duncan Visits Uruguay for a Workshop in Drug Discovery for Neglected Diseases and Malaria

Duncan teams up with Prof Simon Croft and Dr Vanessa Yardley (London School for Hygiene and Tropical Medicine) to visit Gloria Serra and her colleagues at the Facultad de Química, Universidad de la República de Uruguay, Montevideo. We discussed distributed manufacturing approaches and flow chemistry to combat Malaria, Chagas disease, Trypanosomiasis and Leishmaniasis.

Friday, 1 April 2016

New Member - Yerbol Sagatov Joins The Browne Research Group

The Browne lab welcomes new M.Phil. Student Yerbol Sagatov. Yerbol arrives on a Bolashak International Scholarship of the President of the Republic of Kazakhstan and has spent a year at the London School of Economics. Yerbol will eat you for breakfast!...... if you consist of eggs, beans, bacon, sausage, toast & hash browns, Yerbol likes to start the day with one (occasionally two!) British breakfasts.

Friday, 18 March 2016

New Member - Abdul Hadi Aldmairi Joins The Browne Research Group

The Browne lab welcomes Visiting Scholar Dr Abdul Hadi Aldmairi. Abdul obtained his PhD with Prof David Knight working on the synthesis of natural products using proton catalysed cyclisation reactions. Abdul will explore flow methods and organo-fluorine chemistry. Abdul likes to eat a lemon-a-day!

Wednesday, 16 March 2016

Duncan Gives a Lecture at SCI/RSC Continuous Flow Technology III @ Robinson College Cambridge

Duncan attends and gives a lecture at the 3rd in the series of UK conferences on Continuous Flow Processing. It was exciting to meet so many people and exciting to see that the industrialists continue to take the bull-by-the-horns with flow chemistry. It was also clear that the next generation of undergraduates and graduate students with training in continuous flow processing would be attractive to industry!

Tuesday, 16 February 2016

Browne Group Present at 6th International Flow Chemistry Conference, Cambridge

The group attend a busy 6th International Flow Chemistry Conference at Magdalene College, Cambridge. Where Duncan gave a lecture on the recent flow work from the group and Christiane and Joey presented posters. We enjoyed meeting many old and new faces and the live demo of remote control from the Ley Lab, nice job JSP and Daniel!

Wednesday, 20 January 2016

New Members - Hassan Akram & Martyn Shepherd Join The Browne Research Group

The Browne lab welcomes B.Sc. students Hassan Akram & Martyn Shepherd who join the group for their final year projects.

Thursday, 7 January 2016

New Publication

Our work is published in the new RSC journal Reaction Chemistry and Engineering on a continuous flow machine for the multistep synthesis of pyrazoles including the synthesis of Celcoxib. Good job JSP!

J.-S. Poh, D. L. Browne*, S. V. Ley React. Chem. Eng. 2016 DOI: 10.1039/C5RE00082C.

Wednesday, 7 October 2015

New Member - Tiphaine Chenilleau Joins the Browne Research Group

The Browne Group welcomes ERASMUS Student Tiphaine Chenilleau from Université de Nantes. Tiphaine joins us for the academic year.

Thursday, 1 October 2015

New Member - David Cutress Joins the Browne and Brophy (Aberystwyth) Research Groups

The Browne Group welcomes PhD Student David J. Cutress who joins the Browne, and Brophy (Aberystwyth) groups. Davids PhD is sponsored by the NRN Life Science Research Network Wales . David has the exciting/daunting (delete as appropriate) task of designing, synthesising and testing compounds that may inhibit liver fluke (a liver parasite). Davids project is entitled 'Towards validation of an immune suppressor protein from liver fluke as a drug target'. David studied genetics and biochemistry at Aberystwyth University IBERS receiving a first class degree along with the 'Society of Biology Top Student Award' after finishing his degree he was granted the 'Walter Idris Jones' bursary for a joint lab based project with the Geology and Microbiology departments studying novel glacial microbe species, in particular exosome vesicle activities.

Monday, 28 September 2015

New Member - Toby Sydenham Joins the Browne, Fallis & Amaroso Research Groups

The Browne Group welcomes MChem Student Toby Sydenham who joins the Browne, Fallis and Amaroso groups for his final year project.....3 supervisors, I didn't think anyone would pick that project. Toby does an excellent James Blunt impression!

Wednesday, 23 September 2015

New Members - Stefan Burger & Louis Frentzel-Beyme Join the Browne and Melen Groups

The Browne Group welcomes Stefan Burger an ERASMUS student coming from Technische Universität München (TUM) and Louis Frentzel-Beyme an ERASMUS student coming from Ruhr-Universität Bochum. Stefan and Louis join both the Browne and Melen groups for joint collaborative projects.

Monday, 6 July 2015

New Members - Alex Bukvic Joins The Browne Research Group

The Browne lab welcomes Summer student Alex Bukvic who will work on an industrially funded summer studentship. Aside from chemistry Alex enjoys white-water rafting in the south of France, although wouldn't recommend driving in a car that is at the end of its life!

Tuesday, 16 June 2015

New Member - Hubert Meissel Joins The Browne and Hammond Groups

The Browne Group welcomes Hubert Meissel who joins both the Browne and Hammond groups for his Catalysis CDT sabbatical II placement with the Catalysis CDT.

Monday, 15 June 2015

Completion of Projects in The Browne Research Group

June 2015 Congratulations to Stephen (MChem), Gareth (B.Sc.) and Krystie (B.Sc.) who finish up their projects, thanks for all of the hard work.

New Member - Laura Repusseau Joins The Browne Research Group

The Browne Research Group welcomes Laura Repusseau who joins as an ERASMUS summer student from INSA Rouen.

Monday, 1 June 2015

New Member - Quentin Bernard Joins The Browne and Harris Groups

Welcome to Quentin Bernard who joins DLB and Harris groups for 8 weeks from Pierre-Gilles de Gennes École nationale de chimie physique et biologie de Paris!

Tuesday, 26 May 2015

New Publication

Our collaborative work with Ley, Lapkin and Nolan Groups is published – Congratulations Christiane!

C. Schotten, D. Plaza, S. Manzini, S. P. Nolan, S. V. Ley, D. L. Browne*, A. Lapkin* ACS Sustainable Chem. Eng. 2015, 3, 1453-1459.

Tuesday, 12 May 2015

Duncan Gives Lecture at Cardiff Chemistry Conference

DLB gives a Lecture at the 14th Cardiff Chemsitry Conference and the weather holds out for our visiting speakers…..mostly!

Saturday, 9 May 2015

New Publication

DLBs review of the Flow Chemistry textbooks (Vol.1 Fundamentals & Vol.2 Applications) is published in Green Processing and Synthesis

D. L. Browne* Green Process Synth. 2015, 4, 253-253.